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. 1979 Mar 1;92(2):153-9.
doi: 10.1016/0009-8981(79)90109-8.

Short chain fatty acids in plasma and brain: quantitative determination by gas chromatography

C Bachmann, J P Colombo, J Berüter

Short chain fatty acids in plasma and brain: quantitative determination by gas chromatography

C Bachmann et al. Clin Chim Acta. .

Abstract

A reliable and practicable method for the determination of short chain fatty acids in plasma and brain tissue is presented. The sample preparation by partition chromatography on silicic acid allows subsequently a quantitation of short chain fatty acids without interference by methylmalonic acid, or other more polar compounds. With the gas-chromatographic system 2-methylbutyrate is separated from isovalerate. Reference values are given for plasma. The system is also useful in combination with mass spectrometry.

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