Doxantrazole, an antiallergic agent orally effective in man
- PMID: 48779
- DOI: 10.1016/s0140-6736(75)93141-4
Doxantrazole, an antiallergic agent orally effective in man
Abstract
In-vivo studies have demonstrated antiallergic properties in doxantrazole when given orally to rats. These properties were confirmed in work with in-vitro preparations. No significant animal toxicity has been detected. 200 mg. given by mouth inhibited the immediate-type asthmatic response in volunteer patients challenged with specific antigen.
Similar articles
-
Trial of doxantrazole in asthma.Br Med J. 1979 Jan 13;1(6156):92. doi: 10.1136/bmj.1.6156.92. Br Med J. 1979. PMID: 104761 Free PMC article. Clinical Trial. No abstract available.
-
Cold urticaria: inhibition of cold-induced histamine release by doxantrazole.J Invest Dermatol. 1978 Oct;71(4):266-8. doi: 10.1111/1523-1747.ep12515101. J Invest Dermatol. 1978. PMID: 81244 Clinical Trial.
-
Inhibitory effect of oral doxantrazole on asthma induced by allergen inhalation.Br Med J. 1975 Aug 2;3(5978):283-4. doi: 10.1136/bmj.3.5978.283-a. Br Med J. 1975. PMID: 1148776 Free PMC article. Clinical Trial. No abstract available.
-
Antiallergic properties of SQ 13,847, an orally effective agent. II. Activity in vitro.J Pharmacol Exp Ther. 1980 Jun;213(3):437-40. J Pharmacol Exp Ther. 1980. PMID: 6162946
-
A review of the clinical pharmacology of hycanthone.Egypt J Bilharz. 1974;1(1):35-53. Egypt J Bilharz. 1974. PMID: 4619885 Review. No abstract available.
Cited by
-
Comparative effects of oxatomide on the release of histamine from rat peritoneal mast cells.Agents Actions. 1981 May;11(3):184-92. doi: 10.1007/BF01967612. Agents Actions. 1981. PMID: 6167156
-
Trial of doxantrazole in asthma.Br Med J. 1979 Jan 13;1(6156):92. doi: 10.1136/bmj.1.6156.92. Br Med J. 1979. PMID: 104761 Free PMC article. Clinical Trial. No abstract available.
-
Impairment of the intestinal barrier by ethanol involves enteric microflora and mast cell activation in rodents.Am J Pathol. 2006 Apr;168(4):1148-54. doi: 10.2353/ajpath.2006.050617. Am J Pathol. 2006. PMID: 16565490 Free PMC article.
-
Effects of [N-(2-oxo-3,5,7-cycloheptatrien-1-yl)] aminooxoacetic acid ethyl ester (AY-25,674) on cyclic 3',5'-nucleotide formation and phosphodiesterase activity.Experientia. 1979 Jan 15;35(1):88-90. doi: 10.1007/BF01917895. Experientia. 1979. PMID: 217716
-
New light on the mechanism of action of disodium cromoglycate.Agents Actions. 1981 Apr;11(1-2):94-6. doi: 10.1007/BF01991467. Agents Actions. 1981. PMID: 6787851
MeSH terms
Substances
LinkOut - more resources
Full Text Sources