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. 1975 May 24;1(7917):1169-70.
doi: 10.1016/s0140-6736(75)93141-4.

Doxantrazole, an antiallergic agent orally effective in man

J F Batchelor, M J Follenfant, L G Garland, J H Gorvin, A F Green, H F Hodson, D T Hughes, J E Tateson

Doxantrazole, an antiallergic agent orally effective in man

J F Batchelor et al. Lancet. .

Abstract

In-vivo studies have demonstrated antiallergic properties in doxantrazole when given orally to rats. These properties were confirmed in work with in-vitro preparations. No significant animal toxicity has been detected. 200 mg. given by mouth inhibited the immediate-type asthmatic response in volunteer patients challenged with specific antigen.

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