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. 1979 Jul 2;36(2):259-64.
doi: 10.1007/BF00238909.

A method for localized and longlasting microapplication of drugs into nervous tissue of freely moving animals

W Dames, F Joó, J R Wolff

A method for localized and longlasting microapplication of drugs into nervous tissue of freely moving animals

W Dames et al. Exp Brain Res. .

Abstract

A method is described for localized microapplication of drugs into nervous tissue of freely moving rats. Fairly constant release of material was observed over a period of more than three weeks. The amount of substance released was small because the rate of release was determined largely by diffusion rather than by mass movement of solution.

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References

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    1. Nature. 1978 Feb 23;271(5647):761-3 - PubMed
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