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. 1969 Jan;98(1):31-4.
doi: 10.1001/archsurg.1969.01340070049006.

Coagulation during and after orthotopic transplantation of the human liver

C G Groth, L Pechet, T E Starzl

Coagulation during and after orthotopic transplantation of the human liver

C G Groth et al. Arch Surg. 1969 Jan.
No abstract available

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Figures

Fig 1
Fig 1
Measures of coagulation and fibrinolysis in a 13-month-old child who never had satisfactory function of his orthotopic liver homograft. Note that factor VIII remained supernormal while all the liver-based coagulation factors were severely depressed. Euglobulin lysis time (ELT) was infinite.
Fig 2
Fig 2
Intraoperative and early postoperative coagulation changes in a 16-month-old child with life sustaining but impaired immediate homograft function. All coagulation factors studied were depressed below 50% of normal. These gradually returned toward normal. FSP, Fibrinogen split products (see text).
Fig 3
Fig 3
Changes in a 14-month-old child with satisfactory immediate liver function. All coagulation factors studied were transiently but only minimally depressed. FSP, Fibrinogen split products.
Fig 4
Fig 4
Postoperative changes in a 20½-month-old patient. Early homograft function was satisfactory but progressive liver failure due to chronic rejection subsequently developed. During the late course, factor VIII remained supernormal while the liver-based II and V and plasminogen ultimately declined.
See this image and copyright information in PMC

References

    1. Starzl TE, et al. Homotransplantation of the Liver in Humans. Surg Gynec Obset. 1963 Dec;117:659–676. - PMC - PubMed
    1. Von Kaulla KN, et al. Changes in Blood Coagulation Before and After Hepatectomy or Liver Transplantation in Dogs and Man. Arch Surg. 1966 Jan;92:71–79. - PMC - PubMed
    1. Hutchison DE, et al. Platelet Changes Following Clinical and Experimental Hepatic Homotransplantation. Arch Surg. 1968 July;97:27–33. - PMC - PubMed
    1. Pechet L, Groth CG, Daloze PM. Changes in Coagulation and Fibrinolysis After Orthotopic Canine Liver Homotransplantation. J Lab Clin Med. to be published. - PubMed
    1. Blecher TE, Terblanche J, Peacock JH. Orthotopic Liver Homotransplantation. Arch Surg. 1968 March;96:331–339. - PubMed

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