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. 1979 Sep 15;35(9):1152-3.
doi: 10.1007/BF01963255.

The role of sialic acid in 5-HT binding to synaptic membranes

G A Dette, W Wesemann

The role of sialic acid in 5-HT binding to synaptic membranes

G A Dette et al. Experientia. .

Abstract

The high affinity binding of [14C]5-HT to nerve ending membranes isolated from rat brain is not affected by neuraminidase treatment. The specificity of ligand receptor interaction was demonstrated by displacement studies with tryptamine derivatives, noradrenaline, and acetylcholine.

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