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. 1979 Sep 15;35(9):1210-2.
doi: 10.1007/BF01963295.

The localization of [3H]-desipramine in central nerve terminals studied with electron microscope autoradiography and subcellular fractionation

Z Yavin, A Biegon, R Hofstein, D Samuel

The localization of [3H]-desipramine in central nerve terminals studied with electron microscope autoradiography and subcellular fractionation

Z Yavin et al. Experientia. .

Abstract

The cellular and subcellular distribution of [3H]-desipramine (DMI) in rat brain was studied by electron microscope (EM) autoradiography and by subcellular fractionation. A considerable proportion of label was found to be bound to the membranes of presynaptic nerve terminals, as well as to sites inside those terminals.

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