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. 1975 May 31;1(7918):1216-8.
doi: 10.1016/s0140-6736(75)92196-0.

Use of co-trimoxazole in chronic renal failure

P R Tasker, G A MacGregor, H E de Wardener

Use of co-trimoxazole in chronic renal failure

P R Tasker et al. Lancet. .

Abstract

Twenty patients with chronic renal failure and either urinary or respiratory tract infection were treated with co-trimoxazole. Seventeen patients showed no deterioration in renal function while receiving co-trimoxazole. Deterioration in renal function during treatment in the other three patients was due to factors other than administration of the drug. It is concluded that co-trimoxazole can be used in patients with chronic renal failure provided the dose is adjusted according to the degree of renal failure.

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