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. 1969 Apr;41(1):162-6.
doi: 10.1083/jcb.41.1.162.

Isolation and properties of secretory granules from rat islets of Langerhans. II. Ultrastructure of the beta granule

M H Greider, S L Howell, P E Lacy

Isolation and properties of secretory granules from rat islets of Langerhans. II. Ultrastructure of the beta granule

M H Greider et al. J Cell Biol. 1969 Apr.

Abstract

Beta granules isolated from rat islets of Langerhans and subjected only to phosphotungstic acid had, in negatively stained images, a 50-A periodicity. This periodicity was also observed in thin-section profiles of beta granules in intact cells. In shadowed preparations, the granules were spherical in shape and had irregular edges and surface structure. The presence of such a periodicity in the beta granule indicates that its matrix may be composed of a crystalline material.

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References

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