Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1969 Mar;97(3):1298-304.
doi: 10.1128/jb.97.3.1298-1304.1969.

Cold-sensitive mutations in Salmonella typhimurium which affect ribosome synthesis

P C Tai, D P Kessler, J Ingraham

Cold-sensitive mutations in Salmonella typhimurium which affect ribosome synthesis

P C Tai et al. J Bacteriol. 1969 Mar.

Abstract

A number of mutations (45) expressed as cold-sensitive conditional lethal pheno-types were screened by transduction for their linkage to the streptomycin-resistance locus; 7 showed such linkage. Of these, two were studied in greater detail. The sedimentation profiles of ribosomes from cultures grown at low temperature differed from wild type and from one another. Both mutants lost ribonucleic acid control at low temperature. It is suggested that a high proportion of mutants expressing a cold-sensitive phenotype harbor mutations in genes affecting ribosome synthesis or regulation.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. J Mol Biol. 1967 Dec 14;30(2):255-75 - PubMed
    1. J Mol Biol. 1966 Oct 28;21(1):145-71 - PubMed
    1. Bull Soc Chim Biol (Paris). 1965;47(8):1609-26 - PubMed
    1. Proc Natl Acad Sci U S A. 1965 Aug;54(2):451-7 - PubMed
    1. J Bacteriol. 1967 Dec;94(6):1970-81 - PubMed

LinkOut - more resources