doi: 10.1126/science.164.3879.583.
Dye-sensitized photooxidation of the Escherichia coli ribosome
- PMID: 4888105
- DOI: 10.1126/science.164.3879.583
Item in Clipboard
Dye-sensitized photooxidation of the Escherichia coli ribosome
Science.
.
Abstract
Chemical modification of ribosomes from Escherichia coli by oxidation in the presence of selected photosensitizing dyes causes a rapid loss of their amino acid-incorporating ability. By comparing the efficiency of dyes that sensitize the photooxidation of either guanine in ribonucleic acid or amino acid residues in proteins, inactivation of one or more functional ribosomal proteins is inferred.
Similar articles
-
Labilizing action of intercalating drugs and dyes on bacterial ribosomes.Biochemistry. 1972 Apr 25;11(9):1569-72. Biochemistry. 1972. PMID: 4554949 No abstract available.
-
[On the photodynamic action of dyes, VII. Inhibition of RNA synthesis in Saccharomyces cells of different degrees of ploidy by dyes in the presence and absence of visible light].Z Naturforsch B. 1967 Feb;22(2):196-200. Z Naturforsch B. 1967. PMID: 4384717 German. No abstract available.
-
Methylene blue sensitized photoinactivation of E. coli ribosomes: effect on the RNA and protein components.Photochem Photobiol. 1978 Oct-Nov;28(4-5):547-52. doi: 10.1111/j.1751-1097.1978.tb06967.x. Photochem Photobiol. 1978. PMID: 366638 No abstract available.
-
The effects of vital dyes on living organisms with special reference to methylene blue and neutral red.Histochem J. 1971 Jan;3(1):71-93. doi: 10.1007/BF01686508. Histochem J. 1971. PMID: 4106597 Review. No abstract available.
-
3,7-bis(dialkylamino)phenothiazin-5-ium derivatives: biomedical applications and biological activity.Curr Drug Targets. 2003 Feb;4(2):133-41. doi: 10.2174/1389450033346902. Curr Drug Targets. 2003. PMID: 12558066 Review.
Cited by
-
Antimicrobial photodynamic therapy mediated by methylene blue and potassium iodide to treat urinary tract infection in a female rat model.Sci Rep. 2018 May 8;8(1):7257. doi: 10.1038/s41598-018-25365-0. Sci Rep. 2018. PMID: 29740035 Free PMC article.
-
Antimicrobial Photodynamic Inactivation Mediated by Tetracyclines in Vitro and in Vivo: Photochemical Mechanisms and Potentiation by Potassium Iodide.Sci Rep. 2018 Nov 20;8(1):17130. doi: 10.1038/s41598-018-35594-y. Sci Rep. 2018. PMID: 30459451 Free PMC article.
-
Tetracyclines: light-activated antibiotics?Future Med Chem. 2019 Sep;11(18):2427-2445. doi: 10.4155/fmc-2018-0513. Epub 2019 Sep 23. Future Med Chem. 2019. PMID: 31544504 Free PMC article. Review.
-
Nontoxic singlet oxygen generator as a therapeutic candidate for treating tauopathies.Sci Rep. 2015 Jun 1;5:10821. doi: 10.1038/srep10821. Sci Rep. 2015. PMID: 26027742 Free PMC article.
-
Bacterial ribosome.Bacteriol Rev. 1970 Sep;34(3):228-77. doi: 10.1128/br.34.3.228-277.1970. Bacteriol Rev. 1970. PMID: 16350216 Free PMC article. No abstract available.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
