doi: 10.1016/0020-7101(79)90015-1.
Multicompartment pharmacokinetic analysis and simulations using a programmable calculator
- PMID: 489156
- DOI: 10.1016/0020-7101(79)90015-1
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Multicompartment pharmacokinetic analysis and simulations using a programmable calculator
Int J Biomed Comput.
1979 May.
Abstract
This paper describes the use of a programmable calculator (HP-97), for fitting plasma concentration profiles to 1 and 2 compartment open models and calculating fitted and derived parameters together with estimates of steady state plasma drug levels following various dosage regimens in clinical settings.
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