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. 1969 Feb;4(2):227-39.

Cryoglobulins in New Zealand Black mice

W Hijmans, H Radema, L van Es, T E Feltkamp, J J van Loghem, O L Schaap

Cryoglobulins in New Zealand Black mice

W Hijmans et al. Clin Exp Immunol. 1969 Feb.

Abstract

In about a quarter of New Zealand Black mice (NZB mice), aged 4 months or older, cryoglobulins were found, sometimes in large amounts. The frequency was somewhat higher in females than in males. The presence of cryoglobulins was rarely observed in control mice and in these groups the cryocrit always remained low.

The majority of the cryoglobulins in NZB mice were macroglobulins with a relatively positive charge. Attempts to elucidate their significance have remained unsuccessful so far.

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