Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1969 Feb;62(2):574-80.
doi: 10.1073/pnas.62.2.574.

Physiological role of 70S ribosomes in bacteria

I D Algranati, N S Gonzalez, E G Bade

Physiological role of 70S ribosomes in bacteria

I D Algranati et al. Proc Natl Acad Sci U S A. 1969 Feb.

Abstract

Evidence is presented indicating that free 70S ribosomes are real components of Bacillus stearothermophilus and Escherichia coli in exponential and stationary phases of growth. After pulses of radioactive leucine or uracil were given, protein synthesis was instantaneously stopped by chloramphenicol, or polypeptide growth was allowed to proceed to completion in slowly cooled cells. Analysis of label distribution in sucrose gradients showed that 70S monomers, and not subunits, are final products of translation.A ribosome cycle for protein synthesis in bacteria is proposed.

PubMed Disclaimer

References

    1. J Mol Biol. 1965 Sep;13(2):496-510 - PubMed
    1. J Biol Chem. 1967 Mar 10;242(5):1069-73 - PubMed
    1. Nature. 1968 Jul 20;219(5151):232-5 - PubMed
    1. Proc Natl Acad Sci U S A. 1967 Oct;58(4):1560-5 - PubMed
    1. J Mol Biol. 1967 Feb 14;23(3):495-521 - PubMed

LinkOut - more resources