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. 1969 Mar;62(3):934-40.
doi: 10.1073/pnas.62.3.934.

Endonuclease II of E. coli. I. Isolation and purification

E C Friedberg, D A Goldthwait

Endonuclease II of E. coli. I. Isolation and purification

E C Friedberg et al. Proc Natl Acad Sci U S A. 1969 Mar.

Abstract

The isolation and purification of a new endonuclease of E. coli is described. This enzyme degrades alkylated DNA as assayed by a technique that requires double-strand scission. The enzyme also makes a limited number of single-strand breaks in native nonalkylated DNA.

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