Clinical Trial
doi: 10.1136/bmj.4.5677.206.
Topical ampicillin in the appendicectomy wound: report of double-blind trial
- PMID: 4900147
- PMCID: PMC1629853
- DOI: 10.1136/bmj.4.5677.206
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Clinical Trial
Topical ampicillin in the appendicectomy wound: report of double-blind trial
Br Med J.
.
Abstract
One hundred and thirty unselected patients undergoing appendicectomy were treated with topical ampicillin powder or topical placebo powder (lactose) before closing the wound. The postoperative wound infection rates were 3% in the ampicillin-treated group and 24% in the control group, a significant difference. This difference was not influenced by the degree of inflammation in the appendix. No side-effects of treatment were observed.
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