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. 1979 Jul;20(5):669-73.

Isolation and characterization of a heptaglycosylceramide from bovine erythrocyte membranes

  • PMID: 490044
Free article

Isolation and characterization of a heptaglycosylceramide from bovine erythrocyte membranes

J L Chien et al. J Lipid Res. 1979 Jul.
Free article

Abstract

A heptaglycosylceramide was isolated from bovine erythrocyte membranes. The structure was characterized to be Gal(alpha 1-3)Gal(beta 1-4)GlcNAc(beta1-3)Gal(beta 1-4)Glc-NAc(beta 1-4)al(beta 1-4)GlcCer. A hexaglycosylceramide that has the same sequence except for the terminal alpha-galactosyl unit has also been isolated. We have previously found that gangliosides isolated from bovine erythrocyte membranes contain a keratan sulfate type repeating unit --[3Gal(beta 1-4)-GlcNAc beta]--n. This study shows that the keratan sulfate type repeating unit is also present in the neutral glycosphingolipids of bovine erythrocyte membranes.

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