Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1969 Nov;17(5):801-11.

Response to phytohaemagglutinin of lymphocytes from mice treated with anti-lymphocyte globulin

A Tursi, M F Greaves, G Torrigiani, J H Playfair, I M Roitt

Response to phytohaemagglutinin of lymphocytes from mice treated with anti-lymphocyte globulin

A Tursi et al. Immunology. 1969 Nov.

Abstract

Thymus, spleen, lymph node and peripheral blood lymphocytes taken from mice treated with anti-lymphocyte globulin (ALG) showed a greatly diminished response to PHA in vitro. Recovery of circulating lymphocyte levels preceded recovery of responsiveness to PHA. The latter could be prevented by reinjection of ALG or by thymectomy. Grafts were rejected within a period equal to the normal rejection time after PHA responsiveness had recovered to a value of approximately 20 per cent of the normal. Thus the effect of ALG on thymus dependent lymphocytes in mice can be monitored by assessing the PHA sensitivity of peripheral white blood cells.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. J Immunol. 1966 Feb;96(2):217-28 - PubMed
    1. Proc Soc Exp Biol Med. 1966 Mar;121(3):722-5 - PubMed
    1. Lancet. 1967 Feb 4;1(7484):249-51 - PubMed
    1. J Cell Sci. 1967 Mar;2(1):57-70 - PubMed
    1. Nature. 1967 Sep 30;215(5109):1461-4 - PubMed

LinkOut - more resources