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. 1969 Dec;100(3):1311-5.
doi: 10.1128/jb.100.3.1311-1315.1969.

Nonsense mutations in the maltose A region of the genetic map of Escherichia coli

D Hatfield, M Hofnung, M Schwartz

Nonsense mutations in the maltose A region of the genetic map of Escherichia coli

D Hatfield et al. J Bacteriol. 1969 Dec.

Abstract

The isolation of one amber mutation in malQ, one ochre mutation in malP, and seven amber mutations in malT is reported. A study of their phenotypic expressions in the presence of the amber suppressor su(III) and the ochre suppressor su(c) suggests that (i) malQ is the structural gene for amylomaltase; (ii) malQ and the structural gene for maltodextrin phosphorylase, malP, belong to the same operon; (iii) the malT product, which promotes the expression of the malP-malQ operon, is a protein synthesized in limiting amounts by the wild-type strain.

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References

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