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. 1969 Dec;5(6):673-8.

Formalinized chicken red cell nuclei as a simple antigen for standardized antinuclear factor determination

Formalinized chicken red cell nuclei as a simple antigen for standardized antinuclear factor determination

J H ten Veen et al. Clin Exp Immunol. 1969 Dec.

Abstract

Chicken red cell nuclei treated with formalin appear to be specific and easy to handle nuclear antigens for antinuclear factor determination. They can be kept without cooling or freezing for at least 6 months, and probably considerably longer.

As these nuclei can easily be obtained in great amounts it appears feasible to develop an international nuclear standard antigen for standardization in immunofluorescence. They might also be applied as a nuclear antigen in automated antinuclear factor determination.

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