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. 1970 May;5(5):659-61.
doi: 10.1128/JVI.5.5.659-661.1970.

Intracellular inactivation of bacteriophage T4 early deoxyribonucleic acid

Intracellular inactivation of bacteriophage T4 early deoxyribonucleic acid

C K Mathews. J Virol. 1970 May.

Abstract

As previously shown, a small amount of polynucleotide material is added to parental T4 deoxyribonucleic acid (DNA) molecules within the first 5 min of infection. I have asked whether this process is essential for phage replication. Two approaches-one involving decay of (32)P incorporated into this "early DNA" and the other involving photoinactivation of bromodeoxyuridine-containing early DNA-indicate that it is.

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References

    1. Proc Natl Acad Sci U S A. 1963 Sep;50:526-32 - PubMed
    1. J Mol Biol. 1968 Feb 14;31(3):325-48 - PubMed
    1. Biochim Biophys Acta. 1970 Mar 19;204(1):112-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1967 Nov;58(5):2109-16 - PubMed
    1. J Gen Physiol. 1955 Jul 20;38(6):853-65 - PubMed

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