Intracellular inactivation of bacteriophage T4 early deoxyribonucleic acid
- PMID: 4911704
- PMCID: PMC376055
- DOI: 10.1128/JVI.5.5.659-661.1970
Intracellular inactivation of bacteriophage T4 early deoxyribonucleic acid
Abstract
As previously shown, a small amount of polynucleotide material is added to parental T4 deoxyribonucleic acid (DNA) molecules within the first 5 min of infection. I have asked whether this process is essential for phage replication. Two approaches-one involving decay of (32)P incorporated into this "early DNA" and the other involving photoinactivation of bromodeoxyuridine-containing early DNA-indicate that it is.
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