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Clinical Trial
. 1970 May 23;1(5707):458-60.
doi: 10.1136/bmj.2.5707.458.

Clinical trial of the effect of vitamin B12 in elderly subjects with low serum B12 levels

D Hughes, P C Elwood, N K Shinton, R J Wrighton
Clinical Trial

Clinical trial of the effect of vitamin B12 in elderly subjects with low serum B12 levels

D Hughes et al. Br Med J. .

Abstract

A clinical trial of the effect of vitamin B(12) therapy was conducted in 39 elderly subjects who had been found, in a community screening survey, to have low levels of serum B(12) without a macrocytic anaemia or neuropathy. The study produced no evidence which suggests that in such subjects B(12) is superior to placebo in effecting an improvement in psychiatric state or general well-being. There was a clear tendency for all the subjects to show an improvement during the trial, but this probably represents the therapeutic effect of involvement in a research exercise of this kind.

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References

    1. Q J Med. 1965 Jul;34(135):303-17 - PubMed
    1. Br Med J. 1967 Jun 10;2(5553):670-2 - PubMed
    1. Br J Psychiatry. 1967 Mar;113(496):241-51 - PubMed
    1. Br J Psychiatry. 1967 Mar;113(496):252-6 - PubMed
    1. Gerontol Clin (Basel). 1969;11(1):22-35 - PubMed

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