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. 1970 Jul;66(3):716-21.
doi: 10.1073/pnas.66.3.716.

A T4-induced endonuclease which attacks T4 DNA

A T4-induced endonuclease which attacks T4 DNA

S Altman et al. Proc Natl Acad Sci U S A. 1970 Jul.

Abstract

A DNA endonucleolytic activity that introduces single-stranded breaks into native T4 DNA is found in T4-infected E. coli. This endonuclease attacks other double-stranded, but not single-stranded, DNA. Experiments with ultraviolet-irradiated phages and amber mutants indicate that the enzyme is made beginning about five minutes after infection at 37 degrees C.

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