Genetic regulation of ribonucleoside and deoxyribonucleoside catabolism in Salmonella typhimurium
- PMID: 4914068
- PMCID: PMC247604
- DOI: 10.1128/jb.102.3.628-635.1970
Genetic regulation of ribonucleoside and deoxyribonucleoside catabolism in Salmonella typhimurium
Abstract
Four enzymes involved in ribonucleoside and deoxyribonucleoside catabolism (deoxyribose-5-P aldolase, thymidine phosphorylase, phosphodeoxyribomutase, and purine nucleoside phosphorylase) are coded for by four closely linked structural genes on the Salmonella chromosome. The genetic order of these genes is (deoC-deoA-deoB-deoD)-serB-thr. Studies on polarity mutants and induction patterns indicate that the deoB and deoD genes may constitute a single operon and that the deoC and deoA genes may constitute a second closely linked operon.
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