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Clinical Trial
. 1970 Oct 3;4(5726):24-6.
doi: 10.1136/bmj.4.5726.24.

Use of amantadine in Parkinson's disease. Results of a double-blind trial

V Dallos, K Heathfield, P Stone, F A Allen
Clinical Trial

Use of amantadine in Parkinson's disease. Results of a double-blind trial

V Dallos et al. Br Med J. .

Abstract

In a four-week double-blind trial of 62 patients with Parkinsonism 29 were treated withamantadine and 33 with a placebo. Modest but statistically significant improvement was observed in the first group, optimum benefit occurring after the first two weeks. Patients' reactions to the drug were favourable in 79%, and side effects were insignificant. Though amantadine appears to be a useful additive drug in the treatment of Parkinsonism, its value as a single treatment is as yet undetermined.

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References

    1. JAMA. 1969 May 19;208(7):1168-70 - PubMed
    1. Lancet. 1970 Feb 7;1(7641):259-62 - PubMed
    1. Lancet. 1970 Mar 7;1(7645):522 - PubMed
    1. Br Med J. 1970 Feb 21;1(5694):474-5 - PubMed
    1. Lancet. 1970 May 30;1(7657):1127-9 - PubMed

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