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. 1970;42(6):907-10.

Kidney biopsy in the hepatosplenic form of infection with Schistosoma mansoni in man

L C da Silva, T de Brito, M E Camargo, D R de Boni, J D Lopes, J Gunji

Kidney biopsy in the hepatosplenic form of infection with Schistosoma mansoni in man

L C da Silva et al. Bull World Health Organ. 1970.

Abstract

A study of early glomerular lesions was made in 8 patients infected with Schistosoma mansoni but having no clinical evidence of renal disease. Electron-microscopy of renal biopsies showed the presence of electron-dense deposits in basement membranes and of laminated bodies near the mesangial cells. Immunofluorescence showed that the deposits corresponded to IgG in 8 cases and to IgM in 2 cases. These lesions are comparable with those found in the kidneys of patients with cirrhosis of the liver.

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