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. 1970 Dec 11;170(3963):1215-7.
doi: 10.1126/science.170.3963.1215.

Cell interaction in an immune response in vitro: requirement for theta-carrying cells

Cell interaction in an immune response in vitro: requirement for theta-carrying cells

E L Chan et al. Science. .

Abstract

Cytotoxic antiserum to theta antigen reduces the capacity of mouse spleen cells to generate direct and indirect plaque-forming cells to sheep erythrocytes in vitro but does not affect plaque-forming cells, their precursors, or hemopoietic stem cells. The response of spleen cells treated with antiserum to theta antigen is restored by thymus cells incubated in vivo with sheep erythrocytes.

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