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. 1979 Aug 31;5(3):189-91.
doi: 10.1007/BF00778422.

No stimulatory effect of added histones on DNA synthesis in isolated HeLa cell nuclei

E Wist, H Prydz

No stimulatory effect of added histones on DNA synthesis in isolated HeLa cell nuclei

E Wist et al. Mol Biol Rep. .

Abstract

Contrary to some recent reports DNA synthesis in isolated HeLa cell nuclei was not stimulated by the addition of low amounts of histones neither in the presence nor in the absence of cytosol. The individual histone fractions H1, H2A, H2B and H3 also failed to stimulated DNA synthesis.

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