Defective recovery of semi-conservative DNA synthesis in xeroderma pigmentosum cells following split-dose ultraviolet irradiation
- PMID: 492196
- DOI: 10.1016/0027-5107(79)90229-x
Defective recovery of semi-conservative DNA synthesis in xeroderma pigmentosum cells following split-dose ultraviolet irradiation
Abstract
In normal human fibroblasts we observe an enhancement of the recovery of the rate of semi-conservative DNA synthesis after split-dose UV-irradiation relative to a single total UV dose. The enhanced recovery is totally absent in both a xeroderma pigmentosum variant line and two xeroderma pigmentosum lines belonging to complementation groups A and C.
Similar articles
-
Xeroderma pigmentosum variant heterozygotes show reduced levels of recovery of replicative DNA synthesis in the presence of caffeine after ultraviolet irradiation.J Invest Dermatol. 2000 Dec;115(6):981-5. doi: 10.1046/j.1523-1747.2000.00154.x. J Invest Dermatol. 2000. PMID: 11121129
-
Repair of ultraviolet radiation damage in xeroderma pigmentosum cells belonging to complementation group F.Mutat Res. 1981 Feb;80(2):381-8. doi: 10.1016/0027-5107(81)90110-x. Mutat Res. 1981. PMID: 7207491
-
Semi-conservative deoxyribonucleic acid synthesis in unirradiated and ultraviolet-irradiated xeroderma pigmentosum and normal human skin fibroblasts.Mutat Res. 1977 Mar;42(3):433-42. doi: 10.1016/s0027-5107(77)80047-x. Mutat Res. 1977. PMID: 854043
-
Replication of damaged DNA: molecular defect in xeroderma pigmentosum variant cells.Mutat Res. 1999 Oct 22;435(2):111-9. doi: 10.1016/s0921-8777(99)00047-6. Mutat Res. 1999. PMID: 10556591 Review.
-
Xeroderma pigmentosum: recent studies on the DNA repair defects.Arch Pathol Lab Med. 1978 Jan;102(1):3-7. Arch Pathol Lab Med. 1978. PMID: 339872 Review.
Cited by
-
Transient complementation of xeroderma pigmentosum cells by microinjection of poly(A)+ RNA.Proc Natl Acad Sci U S A. 1984 Sep;81(18):5676-9. doi: 10.1073/pnas.81.18.5676. Proc Natl Acad Sci U S A. 1984. PMID: 6207527 Free PMC article.
-
Ultraviolet light-induced chromosomal aberrations in cultured cells from Cockayne syndrome and complementation group C xeroderma pigmentosum patients: lack of correlation with cancer susceptibility.Am J Hum Genet. 1988 Mar;42(3):468-75. Am J Hum Genet. 1988. PMID: 3348214 Free PMC article.
-
DNA semi-conservative synthesis in normal and Fanconi anemia fibroblasts following treatment with 8-methoxypsoralen and near ultraviolet light or with X-rays.Hum Genet. 1985;70(3):236-42. doi: 10.1007/BF00273448. Hum Genet. 1985. PMID: 4018790
-
Similarity in the effect of caffeine on DNA synthesis after UV irradiation between xeroderma pigmentosum variant cells and mouse cells.Jpn J Cancer Res. 1989 Aug;80(8):754-8. doi: 10.1111/j.1349-7006.1989.tb01710.x. Jpn J Cancer Res. 1989. PMID: 2511183 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources