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. 1970 Jul;19(1):169-79.

Allotypic suppression of adult mouse spleen cells

H R Anderson

Allotypic suppression of adult mouse spleen cells

H R Anderson. Immunology. 1970 Jul.

Abstract

Adult mouse spleen cells were transferred into irradiated adult mice with xenogeneic erythrocytes. Antibody-producing cells were measured by the localized haemolysis in gel (LHG) assay. Anti-allotype serum directed against the γG2a allotype of the donor cells, given to the recipients at the same time as antigen and spleen cells, suppressed the plaque-forming cells (PFC) producing antibody of that allotype, and had little effect on the other classes investigated.

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References

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