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. 1971 Jan;8(1):25-36.

A correlative study of immunological phenomena in pernicious anaemia

R G Strickland, S Baur, L A Ashworth, K B Taylor

A correlative study of immunological phenomena in pernicious anaemia

R G Strickland et al. Clin Exp Immunol. 1971 Jan.

Abstract

Twenty patients with established pernicious anaemia have been studied by immunological techniques, in order to determine patterns of gastric antibody production. The presence of such antibodies and the immunoglobulin species in which they occur have been determined in serum, gastric juice and mononuclear inflammatory cells of the gastric mucosa. The lack of correlation found suggests that gastric antibodies in the gastric juice are not derived from serum and that serum and gastric juice antibodies are produced, regardless of immunoglobulin class, in some degree or wholly from different sites.

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References

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