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. 1971 Feb;12(2):93-6.
doi: 10.1136/gut.12.2.93.

Effect of cigarette smoking on human gastric secretory responses

H T Debas, M M Cohen, I B Holubitsky, R C Harrison

Effect of cigarette smoking on human gastric secretory responses

H T Debas et al. Gut. 1971 Feb.

Abstract

The effect of smoking three cigarettes over a one-hour period on the pentagastrinstimulated submaximal plateau of acid and pepsin secretion was observed in 12 healthy human volunteers comprising men and women and smokers and non-smokers. No significant overall change in secretion was observed. In one subject, however, acid secretion was significantly inhibited (p < 0.01) and in one individual significant late stimulation (p < 0.01) of both acid and pepsin was observed.

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