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. 1975 Jun;11(6):1371-4.
doi: 10.1128/iai.11.6.1371-1374.1975.

Systemic amyloidosis in mice inoculated with lyophilized Candida cells

S J Mann, F Blank

Systemic amyloidosis in mice inoculated with lyophilized Candida cells

S J Mann et al. Infect Immun. 1975 Jun.

Abstract

Injection of lyophilized Candida albicans or C. parapsilosis cells induced amyloidosis in outbred CFW mice. The disease process was irreversible, and a significant number of animals died of systemic amyloidosis within 400 days after the last treatment. The techniques described may represent a model system for the study of systemic amyloidosis.

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