Systemic amyloidosis in mice inoculated with lyophilized Candida cells
- PMID: 49301
- PMCID: PMC415224
- DOI: 10.1128/iai.11.6.1371-1374.1975
Systemic amyloidosis in mice inoculated with lyophilized Candida cells
Abstract
Injection of lyophilized Candida albicans or C. parapsilosis cells induced amyloidosis in outbred CFW mice. The disease process was irreversible, and a significant number of animals died of systemic amyloidosis within 400 days after the last treatment. The techniques described may represent a model system for the study of systemic amyloidosis.
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