[Role of glucocorticoids in the mitochondrial DNA replication]
[Article in
Russian]
- PMID: 493255
Item in Clipboard
[Role of glucocorticoids in the mitochondrial DNA replication]
[Article in
Russian]
Probl Endokrinol (Mosk).
1979 Sep-Oct.
Abstract
The liver mitochondrial DNA biosynthesis was found to be enhanced in adrenalectomized rats. Cortisol administration to adrenalectomized rats caused a decrease of the liver mitochondrial DNA biosynthesis. Sedimentation analysis of the mitochondrial DNA in CsCl--EtBr gradient has demonstrated that 3H-thymidine incorporation into the mictochondrial DNA increased mainly in the "open circular" molecules fraction.
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