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. 1979 Sep-Oct;25(5):52-6.

[Role of glucocorticoids in the mitochondrial DNA replication]

[Article in Russian]
A G Minchenko
  • PMID: 493255

[Role of glucocorticoids in the mitochondrial DNA replication]

[Article in Russian]
A G Minchenko. Probl Endokrinol (Mosk). 1979 Sep-Oct.

Abstract

The liver mitochondrial DNA biosynthesis was found to be enhanced in adrenalectomized rats. Cortisol administration to adrenalectomized rats caused a decrease of the liver mitochondrial DNA biosynthesis. Sedimentation analysis of the mitochondrial DNA in CsCl--EtBr gradient has demonstrated that 3H-thymidine incorporation into the mictochondrial DNA increased mainly in the "open circular" molecules fraction.

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