Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1971 Jun;106(3):966-71.
doi: 10.1128/jb.106.3.966-971.1971.

Effect of serine hydroxamate on the growth of Escherichia coli

T Tosa, L I Pizer

Effect of serine hydroxamate on the growth of Escherichia coli

T Tosa et al. J Bacteriol. 1971 Jun.

Abstract

The structural analogue of l-serine, l-serine hydroxamate, inhibited the growth of Escherichia coli K-12. Of the other amino acid hydroxamates tested, only l-lysine hydroxamate reduced the rate of growth. Inhibition of growth by l-serine hydroxamate was rapidly reversed by the addition of l-serine to the bacterial culture or by removal of the analogue by filtration. The reversal of inhibition was specific for l-serine. l-Alanine, glycine, or adenine had no effect on an inhibited culture. No evidence for active transport of the analogue was obtained.

PubMed Disclaimer

References

    1. J Mol Biol. 1966 Dec 28;22(2):305-23 - PubMed
    1. J Biol Chem. 1968 May 10;243(9):2081-9 - PubMed
    1. J Bacteriol. 1969 Mar;97(3):1272-82 - PubMed
    1. J Bacteriol. 1970 Jun;102(3):753-9 - PubMed
    1. J Mol Biol. 1968 Oct 14;37(1):131-49 - PubMed

LinkOut - more resources