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. 1971 Jul;68(7):1493-7.
doi: 10.1073/pnas.68.7.1493.

Nature and self-regulated synthesis of the repressor of the hut operons in Salmonella typhimurium

G R Smith, B Magasanik

Nature and self-regulated synthesis of the repressor of the hut operons in Salmonella typhimurium

G R Smith et al. Proc Natl Acad Sci U S A. 1971 Jul.

Abstract

The enzymes mediating histidine utilization, coded by the hut genes, in Salmonella typhimurium are synthesized from two closely-linked operons. Results presented in this paper show that these operons are regulated by a single repressor protein. The hutC gene, coding for this repressor, is part of one of the operons. Since this same operon is sensitive to the repressor, the repressor apparently represses its own synthesis.

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References

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