Ribosome-catalyzed polyester formation
- PMID: 4934577
- DOI: 10.1126/science.173.3994.340
Ribosome-catalyzed polyester formation
Abstract
Deamination of phenylalanyl-transfer RNA with nitrous acid yields the alpha-hydroxyacyl analog, phenyllactyl-transfer RNA. When this is incubated in a protein-synthesizing system directed by polyuridylic acid, it yields an acid-precipitable, alkali-labile polyester of phenyllactic acid.
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