Baclofen in the treatment of spasticity
- PMID: 4938243
- PMCID: PMC1799146
- DOI: 10.1136/bmj.4.5778.15
Baclofen in the treatment of spasticity
Abstract
Baclofendagger (Lioresal), a derivative of gamma-aminobutyric acid, was introduced in 1966 as a possible treatment for spasticity due to corticospinal tract lesions. Preliminary studies suggested that it may be more effective than other spasmolytic agents currently available, and a double-blind controlled trial in a group of 23 patients against placebo has shown it to be significantly more effective.
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