doi: 10.1126/science.493985.
Tumor location detected with radioactively labeled monoclonal antibody and external scintigraphy
- PMID: 493985
- DOI: 10.1126/science.493985
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Tumor location detected with radioactively labeled monoclonal antibody and external scintigraphy
Science.
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Abstract
Murine teratocarcinomas were located in mice by external gamma-ray scintigraphy with an iodine-125-labeled monoclonal antibody specific to the tumors. The specificity of the method was increased by subtracting the radiation produced by an iodine-125-labeled indifferent monoclonal antibody of the same immunoglobulin class as the tumor-specific antibody.
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