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. 1979 Nov 16;206(4420):844-7.
doi: 10.1126/science.493985.

Tumor location detected with radioactively labeled monoclonal antibody and external scintigraphy

B Ballou, G Levine, T R Hakala, D Solter

Tumor location detected with radioactively labeled monoclonal antibody and external scintigraphy

B Ballou et al. Science. .

Abstract

Murine teratocarcinomas were located in mice by external gamma-ray scintigraphy with an iodine-125-labeled monoclonal antibody specific to the tumors. The specificity of the method was increased by subtracting the radiation produced by an iodine-125-labeled indifferent monoclonal antibody of the same immunoglobulin class as the tumor-specific antibody.

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