Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1971 Sep;22(3):397-400.
doi: 10.1128/am.22.3.397-400.1971.

Quantitative nasal culture: a tool in antibiotic research

R R Martin, A White
Clinical Trial

Quantitative nasal culture: a tool in antibiotic research

R R Martin et al. Appl Microbiol. 1971 Sep.

Abstract

The use of the quantitative nasal culture was investigated as a means of evaluation of new antimicrobial drugs in man. Cyclacillin was somewhat more active in vitro than penicillin G against penicillin G-resistant organisms. Cyclacillin was highly effective in suppressing staphylococci susceptible to penicillin G in nasal carriers but did not suppress staphylococci resistant to penicillin G. Although in previous studies by others cyclacillin was effective in treating mice infected with penicillin G-resistant staphylococci, in the present studies cyclacillin was not effective in suppressing nasal penicillin G-resistant staphylococci in man at doses which markedly suppressed penicillin G-sensitive organisms.

PubMed Disclaimer

References

    1. Acta Med Scand Suppl. 1965;436:1-96 - PubMed
    1. J Lab Clin Med. 1967 Jul;70(1):1-8 - PubMed
    1. J Lab Clin Med. 1968 May;71(5):791-7 - PubMed
    1. Antimicrob Agents Chemother (Bethesda). 1967;7:602-8 - PubMed
    1. Am J Med. 1959 Jul;27(1):26-39 - PubMed

Publication types

MeSH terms

LinkOut - more resources