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. 1971 Dec;70(6):872-5.

Hemodynamic alterations caused during orthotopic liver transplantation in humans

G Pappas, W M Palmer, G L Martineau, I Penn, C G Halgrimson, C G Groth, T E Starzl

Hemodynamic alterations caused during orthotopic liver transplantation in humans

G Pappas et al. Surgery. 1971 Dec.
No abstract available

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Figures

Fig. 1
Fig. 1
Cardiac indices measured before, during, and following orthotopic liver transplantation in six patients. Note the reduction during the anhepatic phase when the inferior vena cava and portal vein were cross-clamped. The indices returned to prehepatectomy levels following revascularization of the new liver.
Fig. 2
Fig. 2
The changes in stroke volume index in the same six patients paralleled the changes in cardiac index seen in Fig. 1.
Fig. 3
Fig. 3
In four patients, the mean arterial pressure fell during the anhepatic phase, whereas it rose in two (G. W. and C. E.). There was an average fall in mean arterial pressure of 18 percent during the anhepatic phase.
Fig. 4
Fig. 4
The peripheral vascular resistance rose during the anhepatic period but returned to pre-existing levels following the transplantation.
See this image and copyright information in PMC

References

    1. Moore FD, Wheeler HB, Demissianos HV, Smith LL, Balankura O, Abel K, Greenberg JB, Dammin GJ. Experimental whole-organ transplantation of the liver and of the spleen. Ann Surg. 1960;152:374. - PMC - PubMed
    1. Picache RS, Kapur BML, Starzl TE. The effect of liver disease on the need for venous decompression during the anhepatic phase of canine orthotopic liver transplantation. Surgery. 1970;67:319. - PMC - PubMed
    1. Starzl TE. Experience in hepatic transplantation. Philadelphia, Pa: W. B. Saunders Company; 1969. (with the assistance of Putnam, C. W.)
    1. Starzl TE, Kaupp HA, Brock DR, Lazarus RE, Johnson RV. Reconstructive problems in canine liver homotransplantation with special reference to the postoperative role of hepatic venous flow. Surg Gynecol Obstet. 1960;111:733. - PMC - PubMed

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