[Changes in the cholinosensitivity of sensomotor cortex neurons during conditioned reflex extinction]
- PMID: 494795
[Changes in the cholinosensitivity of sensomotor cortex neurons during conditioned reflex extinction]
Abstract
Characteristics of neuronal responses of the sensorimotor cortex to ionophoretically administered neuromediators (acetylcholine, L-glutamate) were studied in rabbit in the course of extinction of conditioned defensive reflex. In the majority of neurones the extinction of the conditioned reflex is accompanied by a drop of cholinosensitivity. In a number of neurones the extinction of reflexes either does not change the reaction to acetylcholine, or enhances it. The analysis of these reactions permits to assume the existence of a group of neurones directly involved in the formation, fixation and storage of the temporary connection.