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. 1966 Jun 10;152(3728):1520-1.
doi: 10.1126/science.152.3728.1520.

Light-chain heterogeneity of cold agglutinins

N Costea, V Yakulis, P Heller

Light-chain heterogeneity of cold agglutinins

N Costea et al. Science. .

Abstract

Cold agglutinins with specificity to I or to i antigens of humanadult or cord-blood erythrocytes produced during the course of Mycoplasma pneumoniae infection and infectious mononucleosis contain light chains of K and L types. However, cold agglutinin isolated from the serums of patients with chronic cold-agglutinin hemolytic anemia contains only type K light chains. The experimental evidence suggests that some cold agglutinins contain both types of light chains in the same molecule.

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