Agar-gel precipitin-inhibition test for coccidioidomycosis. II. Serological test antigen studies in agar-gel
- PMID: 4964065
- PMCID: PMC547140
- DOI: 10.1128/am.15.5.1054-1061.1967
Agar-gel precipitin-inhibition test for coccidioidomycosis. II. Serological test antigen studies in agar-gel
Abstract
In this study of saprophytic and parasitic growth-phase extracts of Coccidioides immitis, an antigen from the spherule culture supernatant fluid detected a specific antibody in heretofore serologically negative suspect coccidioidomycosis human sera when diffused in agar-gel. This antigen-antibody reaction occurred also in some of the serologically positive human coccidioidomycosis sera. This study indicates that this antigen-antibody reaction should be utilized as a possible routine serological test for complete serodiagnosis.
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