Comparative control of a branch-point enzyme in microorganisms
- PMID: 4964483
- PMCID: PMC276866
- DOI: 10.1128/jb.94.5.1582-1593.1967
Comparative control of a branch-point enzyme in microorganisms
Abstract
Thirty-two genera of microorganisms were identified with one of six distinctive control patterns for the enzyme 3-deoxy-d-arabino-heptulosonate-7-phosphate synthetase. These patterns included sequential feedback inhibition, isoenzyme feedback inhibition, cumulative feedback inhibition, and three (apparent) simple one-effector patterns. Documentation is provided of an overwhelming tendency for control patterns to be strongly conserved among the member species of the various genera that were examined.
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