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. 1968 Feb;95(2):444-8.
doi: 10.1128/jb.95.2.444-448.1968.

Polynucleotide homologies of Brucella deoxyribonucleic acids

B H Hoyer, N B McCullough

Polynucleotide homologies of Brucella deoxyribonucleic acids

B H Hoyer et al. J Bacteriol. 1968 Feb.

Abstract

Deoxyribonucleic acids (DNA's) extracted from organisms presently placed in the genus Brucella (B. abortus, B. melitensis, B. neotomae, and B. suis) possessed very similar polynucleotide sequences. Unlabeled, single-stranded DNA fragments from B. abortus, B. melitensis, B. neotomae, and B. suis were equally effective in competing with the interaction of corresponding radiolabeled, single-stranded DNA fragments with their homologous DNA-agars. Unlabeled fragments of B. ovis, however, did not compete as effectively as the homologous, unlabeled DNA's, and this organism, therefore, had a detectably different polynucleotide composition. The mole percentages of guanine plus cytosine in Brucella DNA's (56 to 58%) were also similar. DNA's from Francisella tularensis, Escherichia coli, and the slow loris did not compete.

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References

    1. Proc Natl Acad Sci U S A. 1964 Oct;52:1053-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1962 Aug;48:1390-7 - PubMed
    1. Proc Natl Acad Sci U S A. 1964 Oct;52:915-22 - PubMed
    1. J Mol Biol. 1965 Mar;11:476-90 - PubMed
    1. Science. 1964 May 22;144(3621):959-67 - PubMed

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