The subcellular distribution and some properties of the cytochrome b component of the microbicidal oxidase system of human neutrophils
- PMID: 496906
- PMCID: PMC1161247
- DOI: 10.1042/bj1820181
The subcellular distribution and some properties of the cytochrome b component of the microbicidal oxidase system of human neutrophils
Abstract
A novel cytochrome b has recently been described in human neutrophils. The subcellular distribution of this cytochrome was investigated by analytical fractionation on continuous sucrose gradients and it was found to have a dual localization, the major component having a similar distribution to the plasma-membrane marker [3H]concanavalin A, and a denser peak located with the specific granules. The two components were separated on discontinuous gradients and studied independently.
Similar articles
-
Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation.J Cell Biol. 1983 Jul;97(1):52-61. doi: 10.1083/jcb.97.1.52. J Cell Biol. 1983. PMID: 6408102 Free PMC article.
-
Changes in the subcellular distribution of the cytochrome b-245 on stimulation of human neutrophils.Biochem J. 1984 Apr 1;219(1):233-42. doi: 10.1042/bj2190233. Biochem J. 1984. PMID: 6721852 Free PMC article.
-
Studies on the subcellular organelles of neutrophils in chronic granulocytic leukaemia with special reference to alkaline phosphatase.Br J Haematol. 1979 Apr;41(4):533-43. doi: 10.1111/j.1365-2141.1979.tb05891.x. Br J Haematol. 1979. PMID: 285720
-
Identification of a previously undescribed cytochrome b in human neutrophils and its relationship to phagocytosis-induced oxidase activity [proceedings].Biochem Soc Trans. 1979 Feb;7(1):187-8. doi: 10.1042/bst0070187. Biochem Soc Trans. 1979. PMID: 437271 No abstract available.
-
Subcellular localization of NAD(P)H oxidase(s) in human neutrophilic polymorphonuclear leucocytes.Biochem J. 1978 Oct 15;176(1):175-8. doi: 10.1042/bj1760175. Biochem J. 1978. PMID: 728106 Free PMC article.
Cited by
-
Development of cytochrome b and an active oxidase system in association with maturation of a human promyelocytic (HL-60) cell line.J Cell Biol. 1982 Dec;95(3):720-6. doi: 10.1083/jcb.95.3.720. J Cell Biol. 1982. PMID: 6296156 Free PMC article.
-
The superoxide-generating oxidase of leucocytes. NADPH-dependent reduction of flavin and cytochrome b in solubilized preparations.Biochem J. 1984 Oct 15;223(2):337-44. doi: 10.1042/bj2230337. Biochem J. 1984. PMID: 6497852 Free PMC article.
-
The mechanism of proton translocation driven by the respiratory nitrate reductase complex of Escherichia coli.Biochem J. 1980 Jul 15;190(1):79-94. doi: 10.1042/bj1900079. Biochem J. 1980. PMID: 6255943 Free PMC article.
-
Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase.Biochem J. 1993 Feb 15;290 ( Pt 1)(Pt 1):41-9. doi: 10.1042/bj2900041. Biochem J. 1993. PMID: 8439298 Free PMC article.
-
Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation.J Cell Biol. 1983 Jul;97(1):52-61. doi: 10.1083/jcb.97.1.52. J Cell Biol. 1983. PMID: 6408102 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources