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. 1979 Jul 15;182(1):181-8.
doi: 10.1042/bj1820181.

The subcellular distribution and some properties of the cytochrome b component of the microbicidal oxidase system of human neutrophils

The subcellular distribution and some properties of the cytochrome b component of the microbicidal oxidase system of human neutrophils

A W Segal et al. Biochem J. .

Abstract

A novel cytochrome b has recently been described in human neutrophils. The subcellular distribution of this cytochrome was investigated by analytical fractionation on continuous sucrose gradients and it was found to have a dual localization, the major component having a similar distribution to the plasma-membrane marker [3H]concanavalin A, and a denser peak located with the specific granules. The two components were separated on discontinuous gradients and studied independently.

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